Article
Atypical arrhythmic complications in familial hypokalemic periodic paralysis.
Journal of cardiovascular medicine (Hagerstown, Md.) - 1 Jan 2009
Maffè Stefano, Signorotti Fabiana, Perucca Antonello, Bielli Massimo, Hladnik Uros, Ragazzoni Elena, Maduli Elisabetta, Paffoni Paola, Dellavesa Pierfranco, Paino Anna Maria, Zenone Franco, Parravicini Umberto, Pardo Nicolò Franchetti, Cucchi Lorenzo, Zanetta Marco
Abstract excerpt
Familial hypokalemic periodic paralysis is an autosomal dominant muscle disorder characterized by episodic attacks of muscle weakness, accompanied by a decrease in blood potassium levels. It is based on genetic mutations in the genes CACNA1S (most frequent, encoding the skeletal muscle calcium channel) and SCN4A (10% of cases, encoding the sodium channel). Few cases have been reported with cardiac dysrhythmia. We...
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