Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling Pathway

25 Aug 2009

Abstract excerpt

Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, are usually benign, and are frequently associated with neurofibromatosis type 2. Here, we define a typical human meningioma microRNA (miRNA) profile and characterize the effects of one downregulated miRNA, miR-200a, on tumor growth. Elevated levels of miR-200a inhibited meningioma cell growth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to MicroRNA in disease regulation
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19703993
DOI: 10.1128/mcb.00332-09

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling PathwayPMID 19703993Read ↗

The biological and diagnostic roles of MicroRNAs in meningiomasSemantic proximity Read ↗

Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAsSemantic proximity Read ↗

Comprehensive Molecular Profiling Identifies FOXM1 as a Key Transcription Factor for Meningioma ProliferationSemantic proximity Read ↗

Gene therapy and nanomedicine for meningioma treatmentSemantic proximity Read ↗

A microRNA expression signature predicts meningioma recurrenceSemantic proximity Read ↗

miR-200a-mediated suppression of non-muscle heavy chain IIb inhibits meningioma cell migration and tumor growth in vivoSemantic proximity Read ↗

Investıgatıon of The Dıagnostıc and Prognostıc Values of Some Specıfıc mıcroRNAs In Menıngıom TumorsSemantic proximity Read ↗

Molecular Genetics of Intracranial Meningiomas with Emphasis on Canonical Wnt SignallingSemantic proximity Read ↗

MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuRSemantic proximity Read ↗

GATA-4, a potential novel therapeutic target for high-grade meningioma, regulates miR-497, a potential novel circulating biomarker for high-grade meningiomaSemantic proximity Read ↗

Microarray‐based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progressionSemantic proximity Read ↗

miR-153-5p suppresses the proliferation, invasion and migration of malignant meningioma via the MEK/ERK signaling pathway by targeting GAB1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.