Intraepidermal but not dermal T lymphocytes are positive for a cell-cycle-associated antigen (Ki-67) in mycosis fungoides.

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Article

Intraepidermal but not dermal T lymphocytes are positive for a cell-cycle-associated antigen (Ki-67) in mycosis fungoides.

The American journal of pathology - 1 Feb 1990

Nickoloff B J, Griffiths C E

Abstract excerpt

The Ki-67 antibody, which reacts with nuclei of actively proliferating cells, was used in an immunohistochemical study to determine if there was any difference between T cells located in the epidermis rather than the dermis, in mycosis fungoides. In 12 of 14 cases of patch/plaque stage mycosis fungoides, the epidermal T cells were Ki-67 positive, while the dermal T cells were Ki-67 negative in all cases. Both...

Topics

Antigens, Differentiation
Antigens, Surface
Cell Adhesion Molecules
Cell Cycle
Cell Transformation, Neoplastic
Humans
Immunohistochemistry
Intercellular Adhesion Molecule-1
Keratinocytes
Ki-67 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocyte Activation

Lymphocyte Function-Associated Antigen-1

Mycosis Fungoides

Phenotype

Receptors, Leukocyte-Adhesion

Skin Neoplasms

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 1968314
PMCID: PMC1877393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1968314-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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