Article
Association of human leukocyte antigens with nasopharyngeal carcinoma in high-risk multiplex families in Taiwan.
Human immunology - 1 Nov 2009
Yu Kelly J, Gao Xiaojiang, Chen Chien-Jen, Yang Xiaohong Rose, Diehl Scott R, Goldstein Alisa, Hsu Wan-Lun, Liang Xueying Sharon, Marti Darlene, Liu Mei-Ying, Chen Jen-Yang, Carrington Mary, Hildesheim Allan
Abstract excerpt
An association between specific human leukocyte antigens (HLA) alleles and nasopharyngeal carcinoma (NPC) has been reported for sporadic NPC, but studies of familial NPC are lacking. We evaluated this association with familial NPC in a study of 301 NPC cases and 1010 family and community controls from Taiwan. Class I HLA alleles were characterized using a sequence-based typing protocol. Allele frequencies between...
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