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Article

Inside life of melanoma cell signaling, molecular insights, and therapeutic targets.

Current oncology reports - 1 Sept 2009

Sosman Jeffrey A, Margolin Kim A

Abstract excerpt

Melanoma is one of the fastest growing tumor types in the United States. Immunotherapy and chemotherapy benefit only a few patients with metastatic disease. Therapy targeting a signaling pathway critical to the cancer's growth can provide dramatic benefit in several other malignancies and may be...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Kinases

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-akt

Share to PTEN Phosphohydrolase

Share to TOR Serine-Threonine Kinases

Source

Identifiers

PMID: 19679016
DOI: 10.1007/s11912-009-0054-y

Genes

BRAF
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19679016-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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