Article
Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jan 2009
Yan L, Yanan D, Donglan S, Na W, Rongmiao Z, Zhifeng C
Abstract excerpt
X-ray repair cross complementing 1 (XRCC1) protein plays an important role in base excision repair. Single nucleotide polymorphisms (SNPs) in XRCC1 gene may affect DNA repairing ability and genetic susceptibility to cancer. This study was designed to investigate the correlation of XRCC1 Arg194Trp Arg280His and Arg399Gln SNPs with the risk of gastric cardiac adenocarcinoma (GCA). Genotypes were analyzed by...
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