Article
DNA repair gene XRCC1 polymorphisms, smoking, and esophageal cancer risk.
Cancer detection and prevention - 1 Jan 2004
Yu Hong-Ping, Zhang Xiao-Yong, Wang Xiao-Li, Shi Lu-Yuan, Li Yuan-Yuan, Li Fang, Su Yan-Hua, Wang You-Jie, Lu Bin, Sun Xi, Lu Wen-Hong, Xu Shun-Qing
Abstract excerpt
To investigate the effect of X-ray repair cross complementing 1 (XRCC1) genetic polymorphisms on esophageal cancer risk, we determined XRCC1 polymorphisms at codon 194 (Arg --> Trp) and codon 399 (Arg --> Gln) in 135 patients with esophageal squamous cell carcinoma (ESCC) and 152 normal controls from hospitals. Although polymorphism at codon 194 was not associated with risk for ESCC, we found that the frequency...
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