Article
Alternative RNA splicing in expression of the glutathione synthetase gene in human cells.
Molecular biology reports - 1 Apr 2010
Uchida Marie, Sugaya Maki, Kanamaru Taichi, Hisatomi Hisashi
Abstract excerpt
Ubiquitous free radical production occurs continuously in cells and tissues. Glutathione is the most abundant mammalian antioxidant, and is synthesized by glutathione synthetase (GSS). Therefore, GSS plays an important role in defending the cell against reactive oxygen species. The expression of GSS has been studied in human cells; however, sequence information about alternative splicing variants of GSS mRNA has...
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