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Article

Gastric cardia carcinoma is associated with the promoter -77T>C gene polymorphism of X-ray cross-complementing group 1 (XRCC1).

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Dec 2009

Corso Giovanni, Marrelli Daniele, Pedrazzani Corrado, Machado José Carlos, Mancini Stefano, Seruca Raquel, Roviello Franco

Abstract excerpt

PURPOSE: X-ray repair cross complementing group 1 (XRCC1) is one of the major DNA repair proteins involved in the bas-excision repair pathway. Several single-nucleotide polymorphisms in the XRCC1 gene are identified and related with increased cancer risk development. In particular, the -77T>C polymorphism located on the promoter region relates with lung cancer risk development. The aim of this study is to analyze...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19662459
DOI: 10.1007/s11605-009-0980-x

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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