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Article

Sensitive and accurate detection of copy number variants using read depth of coverage.

Genome research - 1 Sept 2009

Yoon Seungtai, Xuan Zhenyu, Makarov Vladimir, Ye Kenny, Sebat Jonathan

Abstract excerpt

Methods for the direct detection of copy number variation (CNV) genome-wide have become effective instruments for identifying genetic risk factors for disease. The application of next-generation sequencing platforms to genetic studies promises to improve sensitivity to detect CNVs as well as inve...

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Identifiers

PMID: 19657104
DOI: 10.1101/gr.092981.109
PMCID: PMC2752127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19657104-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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