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Article

Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 5 Aug 2009

Yamashita Tetsuji, Liu Jiewu, Gao Jiangang, LeNoue Sean, Wang Changguan, Kaminoh Jack, Bowne Sara J, Sullivan Lori S, Daiger Stephen P, Zhang Kang, Fitzgerald Malinda E C, Kefalov Vladimir J, Zuo Jian

Abstract excerpt

Retinitis pigmentosa 1 (RP1) is a common inherited retinopathy with variable onset and severity. The RP1 gene encodes a photoreceptor-specific, microtubule-associated ciliary protein containing the doublecortin (DCX) domain. Here we show that another photoreceptor-specific Rp1-like protein (Rp1L1) in mice is also localized to the axoneme of outer segments (OSs) and connecting cilia in rod photoreceptors,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19657028
DOI: 10.1523/JNEUROSCI.5854-08.2009
PMCID: PMC2748320

Genes

RP1
RP1L1
DCX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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