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Article

Glycogen synthase kinase-3 and Omi/HtrA2 induce annexin A2 cleavage followed by cell cycle inhibition and apoptosis.

Molecular biology of the cell - 1 Oct 2009

Wang Chi-Yun, Lin Yee-Shin, Su Wu-Chou, Chen Chia-Ling, Lin Chiou-Feng

Abstract excerpt

Annexin A2 is involved in multiple cellular processes, including cell survival, growth, division, and differentiation. A lack of annexin A2 makes cells more sensitive to apoptotic stimuli. Here, we demonstrate a potential mechanism for apoptotic stimuli-induced annexin A2 cleavage, which contributes to cell cycle inhibition and apoptosis. Annexin A2 was persistently expressed around the proliferative but not the...

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Identifiers

PMID: 19656851
DOI: 10.1091/mbc.e09-02-0174
PMCID: PMC2754929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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