Article
Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained ORF50 gene expression.
Virology - 15 Sept 2009
Bottero Virginie, Sharma-Walia Neelam, Kerur Nagaraj, Paul Arun George, Sadagopan Sathish, Cannon Mark, Chandran Bala
Abstract excerpt
KSHV vGPCR, a lytic cycle associated protein, induces several signaling pathways leading to the activation of various transcription factors and consequently the expression of cellular and viral genes. Though the role of vGPCR in KSHV tumorigenicity has been well studied, its function related to t...
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