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Article

Population dynamics of genetically diverse Plasmodium falciparum lineages: community-based prospective study in rural Amazonia.

Parasitology - 1 Sept 2009

Orjuela-Sánchez P, Da Silva-Nunes M, Da Silva N S, Scopel K K G, Gonçalves R M, Malafronte R S, Ferreira M U

Abstract excerpt

Temporal changes in the prevalence of antigenic variants in Plasmodium falciparum populations have been interpreted as evidence of immune-mediated frequency-dependent selection, but evolutively neutral processes may generate similar patterns of serotype replacement. Over 4 years, we investigated the population dynamics of P. falciparum polymorphisms at the community level by using 11 putatively neutral...

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Identifiers

PMID: 19631016
DOI: 10.1017/S0031182009990539
PMCID: PMC2849677

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