Article
Manganese superoxide dismutase and chemokine genes polymorphisms in chinese patients with anterior uveitis.
Investigative ophthalmology & visual science - 1 Dec 2009
Lan Chenghong, Tam Pancy O S, Chiang Sylvia W Y, Chan Carmen K M, Luk Fiona O J, Lee Gary K Y, Ngai Jasmine W S, Law Jason S S, Lam Dennis S C, Pang Chi-Pui, Lai Timothy Y Y
Abstract excerpt
PURPOSE: To investigate the association of single-nucleotide polymorphisms (SNPs) in the manganese superoxide dismutase (MnSOD) and two chemokine genes (CCL2 and CCL5) in patients with anterior uveitis (AU). METHODS: Seventy-nine Chinese patients with acute AU were recruited, and genotyping of four SNPs including MnSOD 47, CCL2 -2518, CCL2 -2076, and CCL5 -403 alleles was performed with SNP genotyping assays. The...
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