Article
[Clinicopathological diagnosis of gliomas by genotype analysis].
Brain and nerve = Shinkei kenkyu no shinpo - 1 Jul 2009
Nakamura Mitsutoshi, Shimada Keiji, Nakase Hiroyuki, Konishi Noboru
Abstract excerpt
Currently, the use of microscopical examinations alone is insufficient for the histological classification and grading of gliomas. In recognition of the emerging role of molecular diagnostic approaches to glioma classification, the role of genetic profiles has been emphasized on, as in the distinct subtypes of glioma. Glioblastomas (WHO grade IV) may develop de novo (primary glioblastomas) or through progression...
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