Article
Polymorphisms in the promoter region of bovine PRKAB1 gene.
Molecular biology reports - 1 Jan 2010
Zhang Qin, Chen Hong, Zhao Sheng, Zhang Li, Zhang Liangzhi, Wang Xueming
Abstract excerpt
The AMP-activated protein kinase (AMPK) is an evolutionarily conserved sensor of cellular and systemic energy balance. PRKAB1, the gene that encodes the beta1 regulatory subunit of AMPK, has been shown to be highly involved in the glycogen metabolism. To date, several mutations affecting function of human PRKAB1 have been identified, but few studies have shown a complete description of variability of the promoter...
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