Article
Six cases of SCA3/MJD patients that mimic hereditary spastic paraplegia in clinic.
Journal of the neurological sciences - 15 Oct 2009
Wang Yin-guang, Du Juan, Wang Jun-ling, Chen Juan, Chen Chong, Luo Ying-ying, Xiao Zhi-quan, Jiang Hong, Yan Xin-xiang, Xia Kun, Pan Qian, Tang Bei-sha, Shen Lu
Abstract excerpt
BACKGROUND: Spinocerebellar ataxia type 3/Machado-Joseph disease (SCA3/MJD) is an autosomal dominant neurodegenerative disease characterized by cerebellar ataxia associated with varying phenotypic variability. It was reported that a few of SCA3/MJD patients showed marked spastic paraplegia with or without cerebellar ataxia, which was partially first diagnosed as hereditary spastic paraplegia (HSP) and considered...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.