Article
High, clustered, nucleotide diversity in the genome of Anopheles gambiae revealed through pooled-template sequencing: implications for high-throughput genotyping protocols.
BMC genomics - 16 Jul 2009
Wilding Craig S, Weetman David, Steen Keith, Donnelly Martin J
Abstract excerpt
BACKGROUND: Association mapping approaches are dependent upon discovery and validation of single nucleotide polymorphisms (SNPs). To further association studies in Anopheles gambiae we conducted a major resequencing programme, primarily targeting regions within or close to candidate genes for insecticide resistance. RESULTS: Using two pools of mosquito template DNA we sequenced over 300 kbp across 660 distinct...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.