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Article

Association between ACE gene I/D polymorphisms and hyperandrogenism in women with polycystic ovary syndrome (PCOS) and controls.

BMC medical genetics - 14 Jul 2009

Sun Jing, Fan Haijian, Che Yena, Cao Yunxia, Wu Xiaoke, Sun Hai-xiang, Liang Fengjing, Yi Long, Wang Yong

Abstract excerpt

BACKGROUND: I/D polymorphisms of ACE are associated with the plasma ACE concentration. The ACE is associated with the angiogenesis of ovarian endothelium in vitro as well as steroidogenesis and follicular growth in cattle. Since ACE induces a high blood supply and hypersteroidogenesis in the ovary, it may be associated with polycystic ovary syndrome (PCOS) which exhibits hyperplasia, hypervascularity of the...

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Source

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Identifiers

PMID: 19602270
DOI: 10.1186/1471-2350-10-64
PMCID: PMC2714507

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between ACE gene I/D polymorphisms and hyperandrogenism in women with polycystic ovary syndrome (PCOS) and controls.PMID 19602270Read ↗

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Association of angiotensin converting enzyme (ACE) gene I/D polymorphism and polycystic ovary syndrome (PCOS).Semantic proximity Read ↗

Increased frequency of the DI genotype of the angiotensin-I converting enzyme and association of the II genotype with insulin resistance in polycystic ovary syndrome.Semantic proximity Read ↗

Angiotensin Converting Enzyme (ACE) Gene I/D Polymorphism Is Significantly Associated with Insulin Resistance and Polycystic Ovary Syndrome: A Meta-Analysis.Semantic proximity Read ↗

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Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with polycystic ovary syndrome: a meta-analysis.Semantic proximity Read ↗

Do ACE I/D gene polymorphism serve as a predictive marker for age at onset in PCOS?Semantic proximity Read ↗

Associations of ACE I/D, AGT M235T gene polymorphisms with pregnancy induced hypertension in Chinese population: a meta-analysis.Semantic proximity Read ↗

Angiotensin-converting enzyme D/I and plasminogen activator inhibitor-1 4G/5G gene polymorphisms are associated with increased risk of spontaneous abortions in polycystic ovarian syndrome.Semantic proximity Read ↗

Angiotensin I-converting enzyme insertion-related genotypes and allele are associated with higher susceptibility of endometriosis and leiomyoma.Semantic proximity Read ↗

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