Article
Angiotensin I-converting enzyme insertion-related genotypes and allele are associated with higher susceptibility of endometriosis and leiomyoma.
Molecular reproduction and development - 1 Jul 2007
Hsieh Yao-Yuan, Lee Cheng-Chun, Chang Chi-Chen, Wang Yu-Kuo, Yeh Lian-Shun, Lin Chich-Sheng
Abstract excerpt
Endometriosis and leiomyoma display features similar to malignancy, requiring neovascularization to proliferation and growth. Altered vascular-related genes might be related to the development of endometriosis and leiomyoma. Polymorphisms of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) genes have been linked with some vascular diseases. This study investigates whether ACE I/D gene...
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