Article
Vitamin D receptor gene polymorphism(s) and breast cancer risk in north Indians.
Cancer detection and prevention - 1 Jan 2009
Chakraborty Anurupa, Mishra Ashwani K, Soni Abha, Regina Thodum, Mohil R, Bhatnagar D, Bhatnagar A, Chintamani Chintamani, Sharma P C, Saxena Sunita
Abstract excerpt
BACKGROUND: Vitamin D (1,25-dihydroxyVitamin D3) has shown experimentally anticarcinogenic effects and is thought to protect against breast cancer. The actions of Vitamin D are mediated via the Vitamin D receptor (VDR), and the polymorphisms at 3'UTR region of this gene are associated with the risk and progression of breast carcinoma. The current study is an attempt to examine the association of these variations...
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