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Article

Effect of basic fibroblast growth factor (FGF2) gene polymorphisms on SSRIs treatment response and side effects.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Oct 2009

Kato Masaki, Okugawa Gaku, Wakeno Masataka, Takekita Yoshiteru, Nonen Shinpei, Tetsuo Shinji, Nishida Keiichiro, Azuma Junichi, Kinoshita Toshihiko, Serretti Alessandro

Abstract excerpt

Antidepressant response usually appears in 2 to 4 weeks and 30-40% of patients do not show a significant response although biochemical changes of monoaminergic system occur within hours after administration. Genetic factors could play a role in this process and genes involved in synaptic plasticity and neurogenesis are possible candidates. In fact, antidepressants and electroconvulsive therapy increase basic...

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Identifiers

PMID: 19586755
DOI: 10.1016/j.euroneuro.2009.06.006

Genes

FGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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