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Article

CTNNB1 (beta-catenin) mutation is rare in brain tumours but involved as a sporadic event in a brain metastasis.

Acta neurochirurgica - 1 Sept 2009

Lee Chu-I, Hsu Meng-Yu, Chou Chia-Hua, Wang Chihuei, Lo Yu-Shung, Loh Joon-Khim, Howng Shen-Long, Hong Yi-Ren

Abstract excerpt

BACKGROUND: The Wnt signaling pathway has been implicated in colon and other cancers. Nevertheless, few or no mutations of CTNNB1 (beta-catenin) have so far been described in brain cancer. We therefore examined the prevalence of constitutive activation of the Wnt signaling pathway in brain cancer specimens as well as cancer cell lines. METHOD: We used polymerase chain reaction PCR and direct sequencing methods to...

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Source

Identifiers

PMID: 19582367
DOI: 10.1007/s00701-009-0242-4

Genes

CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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