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Genetic rearrangement MLL/AF4 is most frequent in children with acute lymphoblastic leukemias in Mexico City.

Leukemia & lymphoma - 1 Aug 2009

Daniel-Cravioto Alondra, Gonzalez-Bonilla Cesar R, Mejia-Arangure Juan Manuel, Perez-Saldivar Maria Luisa, Fajardo-Gutierrez Arturo, Jimenez-Hernandez Elva, Hernandez-Serrano Milagros, Bekker-Mendez Vilma Carolina

Abstract excerpt

One of the highest incidences of acute lymphoblastic leukemia (ALL) in the world has been reported in Mexico City. In the current study (26 cases), the frequencies of the most frequent genetic rearrangements TEL-AML1, MLL/AF4, BCR-ABL (major and minor) in ALL in children from Mexico City were determined. For the ALL, the frequency of MLL/AF4 was 65.4%, for TEL-AML1 and that of BCR/ABL was 3.8%. Only 6 of the 17...

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PMID: 19579075
DOI: 10.1080/10428190903015636

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BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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