Article
Inhibition of thoughts and actions in obsessive-compulsive disorder: extending the endophenotype?
Psychological medicine - 1 Feb 2010
Morein-Zamir S, Fineberg N A, Robbins T W, Sahakian B J
Abstract excerpt
BACKGROUND: Obsessive-compulsive disorder (OCD) has been associated with impairments in stop-signal inhibition, a measure of motor response suppression. The study used a novel paradigm to examine both thought suppression and response inhibition in OCD, where the modulatory effects of stimuli relevant to OCD could also be assessed. Additionally, the study compared inhibitory impairments in OCD patients with and...
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