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The Evolution of Viruses in Multi-Host Fitness Landscapes

2 Apr 2009

Abstract excerpt

Provided that generalist viruses will have access to potentially unlimited hosts, the question is why most viruses specialize in few hosts. It has been suggested that selection should favor specialists because there are tradeoffs limiting the fitness of generalists in any of the alternative hosts or because evolution proceeds faster with narrower niches. Here we review experiments showing that virus adaptation to...

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PMID: 19572052
DOI: 10.2174/1874357900903010001

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