Article
Apolipoprotein E polymorphism in hemodialyzed patients and healthy controls.
Biochemical genetics - 1 Oct 2009
Hubacek Jaroslav A, Bloudickova Silvie, Kubinova Ruzena, Pikhart Hynek, Viklicky Ondrej, Bobak Martin
Abstract excerpt
A possible association between end-stage renal disease (ESRD) and apolipoprotein E (APOE) polymorphism was found in some but not all studies. We have analyzed the APOE genotypes in 995 hemodialyzed patients (cases) and a sample of 6242 healthy individuals (controls) in the Czech Republic. There was a statistically significant difference in the frequency of APOE alleles between cases and controls, with more...
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