Article
Immunohistochemical staining for P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha may complement mucin phenotype of differentiated-type early gastric carcinoma.
Pathology international - 1 Jul 2009
Takano Kabuto, Hasegawa Go, Jiang Shuying, Kurosaki Isao, Hatakeyama Katsuyoshi, Iwanari Hiroko, Tanaka Toshiya, Hamakubo Takao, Kodama Tatsuhiko, Naito Makoto
Abstract excerpt
Hepatocyte nuclear factor 4alpha (HNF4alpha) isoforms in the human stomach have not been fully investigated. The purpose of the present study was to evaluate the expression of P1 and P2 promoter-driven HNF4alpha (P1 and P2-HNF4alpha) in differentiated-type early gastric carcinomas (DEGC). P1- and P2-HNF4alpha expression was examined immunohistochemically both in non-neoplastic mucosa and carcinoma from surgical...
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