Article
Interleukin-6 (G-174C) and tumour necrosis factor-alpha (G-308A) gene polymorphisms in geriatric patients with chronic periodontitis.
Gerodontology - 1 Mar 2010
Costa A M, Guimarães M C M, de Souza Elias Rosa, Nóbrega O T, Bezerra A C B
Abstract excerpt
BACKGROUND AND OBJECTIVE: Periodontitis is a chronic inflammatory disease, and genetic factors may have an important role in its severity. Polymorphisms in the promoter regions of the interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) genes have been reported to cause changes in th...
Topics
- Adenine
- Aged
- Alleles
- Alveolar Bone Loss
- Chronic Periodontitis
- Cytosine
- Disease Progression
- Female
- Gene Frequency
- Genotype
- Gingival Hemorrhage
- Guanine
- Humans
- Interleukin-6
- Periodontal Attachment Loss
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Tumor Necrosis Factor-alpha