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Article

Cytogenetic analysis of a human familial 15p+ marker chromosome.

Genome - 1 Oct 1991

Velázquez M, Visedo G, Ludeña P, de Cabo S F, Sentís C, Fernández-Piqueras J

Abstract excerpt

An extreme variant of a human 15p+ marker chromosome is described in a human family. The short arm of this variant is greatly enriched in ribosomal RNA genes, and there are up to three secondary constrictions potentially active for rRNA transcription. These sites are hypomethylated, whereas the rest of rDNA is highly methylated, as shown by the isoschizomer pair HpaII-MspI. This chromosome variant is similar to...

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Identifiers

PMID: 1955158
DOI: 10.1139/g91-127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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