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Article

Partial hexasomy of chromosome 15.

American journal of medical genetics. Part A - 1 Sept 2003

Huang Bing, Bartley James

Abstract excerpt

Marker chromosomes originating from chromosome 15, often referred to as inv dup(15), is the most common marker chromosome found in humans. The large marker 15 that contains the Prader-Willi syndrome (PWS)/Angelman syndrome (AS) chromosome region is usually associated with an abnormal phenotype of moderate to severe mental retardation, seizures, poor motor coordination, behavioral problems, and mild dysmorphic...

Topics

Adult
Angelman Syndrome
Chromosome Disorders
Chromosome Inversion
Chromosomes, Human, Pair 15
Female
Humans
In Situ Hybridization, Fluorescence
Infant
Infant, Newborn
Karyotyping
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Prader-Willi Syndrome

Pregnancy

Source

Identifiers

PMID: 12923871
DOI: 10.1002/ajmg.a.20182

Genes

GABRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Partial hexasomy of chromosome 15.PMID 12923871Read ↗

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Partial hexasomy for the Prader-Willi-Angelman syndrome critical region due to a maternally inherited large supernumerary marker chromosome.Semantic proximity Read ↗

Molecular and fluorescence in situ hybridization characterization of the breakpoints in 46 large supernumerary marker 15 chromosomes reveals an unexpected level of complexity.Semantic proximity Read ↗

Prader-Willi syndrome with an unusually large 15q deletion due to an unbalanced translocation t(4;15).Semantic proximity Read ↗

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Paternal uniparental disomy in a child with a balanced 15;15 translocation and Angelman syndrome.Semantic proximity Read ↗

Cytogenetic and molecular characterization of inverted duplicated chromosomes 15 from 11 patients.Semantic proximity Read ↗

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Molecular cytogenetic analysis of inv dup(15) chromosomes, using probes specific for the Prader-Willi/Angelman syndrome region: clinical implications.Semantic proximity Read ↗

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The inv dup (15) or idic (15) syndrome (Tetrasomy 15q)Semantic proximity Read ↗

Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromesSemantic proximity Read ↗

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