Article
Plasticity of interstitial cells of cajal: a study in the small intestine of adult Guinea pigs.
Anatomical record (Hoboken, N.J. : 2007) - 1 Jul 2009
Mei Feng, Han Juan, Huang Yue, Jiang Zhong-Yong, Xiong Cheng-Jie, Zhou De-Shan
Abstract excerpt
Although it is well known that the reduction of interstitial cells of Cajal (ICCs) is associated with several gastrointestinal motility disorders in clinic, it is unknown whether the mature ICCs still have an active plasticity in adult mammals. This study focused on the issues of the reduction of ICCs during Imatinib administration and the recovery of ICCs following drug withdrawal in the small intestine of adult...
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