Article
Meta-analysis of six dairy cattle breeds reveals biologically relevant candidate genes for mastitis resistance.
Genetics, selection, evolution : GSE - 15 Jul 2024
Cai Zexi, Iso-Touru Terhi, Sanchez Marie-Pierre, Kadri Naveen, Bouwman Aniek C, Chitneedi Praveen Krishna, MacLeod Iona M, Vander Jagt Christy J, Chamberlain Amanda J, Gredler-Grandl Birgit, Spengeler Mirjam, Lund Mogens Sandø, Boichard Didier, Kühn Christa, Pausch Hubert, Vilkki Johanna, Sahana Goutam
Abstract excerpt
BACKGROUND: Mastitis is a disease that incurs significant costs in the dairy industry. A promising approach to mitigate its negative effects is to genetically improve the resistance of dairy cattle to mastitis. A meta-analysis of genome-wide association studies (GWAS) across multiple breeds for clinical mastitis (CM) and its indicator trait, somatic cell score (SCS), is a powerful method to identify functional...
Topics
- Animals
- Cattle
- Mastitis, Bovine
- Female
- Quantitative Trait Loci
- Genome-Wide Association Study
- Disease Resistance
- Polymorphism, Single Nucleotide
- Breeding