Article
On the diagnosis of CADASIL.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Ampuero Israel, Alegre-Abarrategui Javier, Rodal Izaskun, España Antonio, Ros Raquel, Sendón José Luis Lopez, Galloway Eva García, Cervelló Angeles, Caminero Ana Belén, Zabala Antxon, Erro Elena, Jarauta Fernando, Morlán Lorenzo, López-Valdés Eva, Aladro Yolanda, Seijo Manuel, Rivas Guillermo García, Muñoz David G, de Yébenes Justo García
Abstract excerpt
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a genetic arteriopathy related to Notch3 mutations, is difficult to diagnosis. The goal of this study was to determine the value of clinical, immunohistochemical, and molecular techniques for the diagnosis of CADASIL. Clinical features and the immunohistochemical and molecular findings in 200 subjects with...
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