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Article

The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders.

Trends in neurosciences - 1 Jul 2009

Betancur Catalina, Sakurai Takeshi, Buxbaum Joseph D

Abstract excerpt

Recent advances in genetics and genomics have unveiled numerous cases of autism spectrum disorders (ASDs) associated with rare, causal genetic variations. These findings support a novel view of ASDs in which many independent, individually rare genetic variants, each associated with a very high relative risk, together explain a large proportion of ASDs. Although these rare variants impact diverse pathways, there...

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Identifiers

PMID: 19541375
DOI: 10.1016/j.tins.2009.04.003
PMCID: PMC10354373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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