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Article

Non-invasive prenatal diagnosis by single molecule counting technologies.

Trends in genetics : TIG - 1 Jul 2009

Chiu Rossa W K, Cantor Charles R, Lo Y M Dennis

Abstract excerpt

Non-invasive prenatal diagnosis of fetal chromosomal aneuploidies and monogenic diseases by analysing fetal DNA present in maternal plasma poses a challenging goal. In particular, the presence of background maternal DNA interferes with the analysis of fetal DNA. Using single molecule counting methods, including digital PCR and massively parallel sequencing, many of the former problems have been solved. Digital...

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Identifiers

PMID: 19540612
DOI: 10.1016/j.tig.2009.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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