Applicability of allele/genotype frequency from documented controls for case-control studies on genotypes among Japanese: MTHFR C677T as an example.

Abstract excerpt

In a case-control study, controls have to be selected from the population where cases are identified. However, there is an idea to make common controls applicable for different case-control studies, which could reduce study costs. This study compared methylenetetrahydrofolate reductase C677T among subjects from different studies, to examine the applicability of combined subjects as controls. Case-control studies...

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