Article
Predominance of hepatitis C virus genotype 4 infection and rapid transmission between 1935 and 1965 in the Central African Republic.
The Journal of general virology - 1 Oct 2009
Njouom Richard, Frost Eric, Deslandes Sylvie, Mamadou-Yaya Fleurie, Labbé Annie-Claude, Pouillot Régis, Mbélesso Pascal, Mbadingai Sylvestre, Rousset Dominique, Pépin Jacques
Abstract excerpt
The molecular epidemiology of hepatitis C virus (HCV) in the Central African Republic (CAR) is poorly documented. Thus, we conducted phylogenetic analyses of NS5B gene sequences from 58 HCV-infected inhabitants of a remote area of south-west CAR, which indicated that 48 (82.8%) were infected with genotype 4 (HCV-4), five (8.6%) with genotype 2 and five (8.6%) with genotype 1. HCV-4 strains were highly...
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