Article
Mutation of the membrane-associated M1 protease APM1 results in distinct embryonic and seedling developmental defects in Arabidopsis.
The Plant cell - 1 Jun 2009
Peer Wendy Ann, Hosein Fazeeda N, Bandyopadhyay Anindita, Makam Srinivas N, Otegui Marisa S, Lee Gil-Je, Blakeslee Joshua J, Cheng Yan, Titapiwatanakun Boosaree, Yakubov Bahktiyor, Bangari Bharat, Murphy Angus S
Abstract excerpt
Aminopeptidase M1 (APM1), a single copy gene in Arabidopsis thaliana, encodes a metallopeptidase originally identified via its affinity for, and hydrolysis of, the auxin transport inhibitor 1-naphthylphthalamic acid (NPA). Mutations in this gene result in haploinsufficiency. Loss-of-function mutants show irregular, uncoordinated cell divisions throughout embryogenesis, affecting the shape and number of cotyledons...
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