Testicular adrenal rest tumours in boys, adolescents and adult men with congenital adrenal hyperplasia may be associated with the CYP21A2 mutation.

doi:10.1111/j.1365-2605.2009.00967.x

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Article

Testicular adrenal rest tumours in boys, adolescents and adult men with congenital adrenal hyperplasia may be associated with the CYP21A2 mutation.

International journal of andrology - 1 Jun 2010

Mouritsen Annette, Jørgensen Niels, Main Katharina M, Schwartz Marianne, Juul Anders

Abstract excerpt

Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder with impaired function of the adrenal cortex caused by mutations in the CYP21A2 gene. Deficiency of steroid 21-hydroxylase accounts for 80-95% of CAH cases. Testicular adrenal rest tumours (TART) may be prevalent in up to 95%...

Topics

Adolescent
Adrenal Hyperplasia, Congenital
Adrenal Rest Tumor
Adult
Genes
Genotype
Humans
Male
Mutation
Steroid 21-Hydroxylase
Testis

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