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Article

A systems biology network model for genetic association studies of nicotine addiction and treatment.

Pharmacogenetics and genomics - 1 Jul 2009

Thomas Paul D, Mi Huaiyu, Swan Gary E, Lerman Caryn, Benowitz Neal, Tyndale Rachel F, Bergen Andrew W, Conti David V

Abstract excerpt

OBJECTIVE: Interpreting genome-scale genetic association data, particularly for complex diseases and phenotypes, requires extensive use of prior knowledge across a broad range of potential biological and environmental influences, spanning many scientific subdisciplines. We suggest that known or hypothesized disease risk factors, and causal mechanisms, can be represented using an ontology, a computational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19525886
DOI: 10.1097/FPC.0b013e32832e2ced
PMCID: PMC6485245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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