Article
MTHFR polymorphisms involved in vitamin B12 deficiency associated with atrophic gastritis.
Biochemical genetics - 1 Oct 2009
Palladino Mariangela, Chiusolo Patrizia, Reddiconto Giovanni, Marietti Sara, De Ritis Daniela, Leone Giuseppe, Sica Simona
Abstract excerpt
Genetic polymorphisms affecting methylentetrahydrofolate reductase (MTHFR) activity may influence hematological and neurological dysfunction in cobalamin-deficient patients. We studied the prevalence of C677T and A1298C polymorphisms by analyzing genomic DNA in 30 cobalamin-deficient patients. No significant difference was found in 677 and 1298 genotype distribution with respect to hematological parameters, B12...
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