Article
Red cell glycolytic enzyme disorders caused by mutations: an update.
Cardiovascular & hematological disorders drug targets - 1 Jun 2009
Climent Fernando, Roset Feliu, Repiso Ada, Pérez de la Ossa Pablo
Abstract excerpt
Glycolysis is one of the principle pathways of ATP generation in cells and is present in all cell tissues; in erythrocytes, glycolysis is the only pathway for ATP synthesis since mature red cells lack the internal structures necessary to produce the energy vital for life. Red cell deficiencies have been detected in all erythrocyte glycolytic pathways, although their frequencies differ owing to diverse causes,...
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