Article
Correlative analysis of gene expression profile and prognosis in patients with gliomatosis cerebri.
Cancer - 15 Aug 2009
D'Urso Oscar Fernando, D'Urso Pietro Ivo, Marsigliante Santo, Storelli Carlo, Luzi Giuseppe, Gianfreda Cosimo Damiano, Montinaro Antonio, Distante Alessandro, Ciappetta Pasqualino
Abstract excerpt
BACKGROUND: In modern clinical neuro-oncology, the pathologic diagnoses are very challenging, creating significant clinical confusion and affecting therapeutic decisions and prognosis. METHODS: TP53 and PTEN gene sequences were analyzed, and microarray expression profiling was also performed. The authors investigated whether gene expression profiling, coupled with class prediction methodology, could be used to...
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