Article
A miRNA signature for defining aggressive phenotype and prognosis in gliomas.
PloS one - 1 Jan 2014
Barbano Raffaela, Palumbo Orazio, Pasculli Barbara, Galasso Marco, Volinia Stefano, D'Angelo Vincenzo, Icolaro Nadia, Coco Michelina, Dimitri Lucia, Graziano Paolo, Copetti Massimiliano, Valori Vanna Maria, Maiello Evaristo, Carella Massimo, Fazio Vito Michele, Parrella Paola
Abstract excerpt
Gliomas represent a disparate group of tumours for which there are to date no cure. Thus, there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA (miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours (2 WHO grade III and 22 glioblastomas) by using the Affymetrix GeneChip miRNA...
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