Article
[Molecular mechanisms of induction of innate immunity].
Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2009
Afanas'ev S S, Aleshkin V A, Baĭrakova A L, Voropaeva E A, Nesvizhskiĭ Iu V, Kafarskaia L I, Egorova E A, Afanas'ev M S, Metel'skaia V A, Grechishnikova O G, Kurakova A A
Abstract excerpt
Cellular and molecular mechanisms of congenital immunity at different levels are discussed including single cell expression patterns and intracellular localization of individual TLR, the use of adapter molecules for generation of activation signals in response to microbial and non-microbial pathogens, soluble trap receptors, and intracellular negative regulators.
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