Article
Apoptosis and cancer: mutations within caspase genes.
Journal of medical genetics - 1 Aug 2009
Ghavami S, Hashemi M, Ande S R, Yeganeh B, Xiao W, Eshraghi M, Bus C J, Kadkhoda K, Wiechec E, Halayko A J, Los M
Abstract excerpt
The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead to tumorigenesis, autoimmunity, and other serious health problems. Deregulated apoptosis may als...
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