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Article

MicroRNA Signature of Malignant Mesothelioma with Potential Diagnostic and Prognostic Implications

5 Jun 2009

Abstract excerpt

MicroRNAs (miRNAs) post-transcriptionally regulate the expression of target genes, and may behave as oncogenes or tumor suppressors. Human malignant mesothelioma is an asbestos-related cancer, with poor prognosis and low median survival. Here we report, for the first time, a cross-evaluation of miRNA expression in mesothelioma (MPP-89, REN) and human mesothelial cells (HMC-telomerase reverse transcriptase)....

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Identifiers

PMID: 19502386
DOI: 10.1165/rcmb.2009-0060oc

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