Differential phenotype in Parkinson's disease patients with severe versus mild GBA mutations

Abstract excerpt

Sir, We read with much interest the comprehensive study by Neumann et al. (2009), published in Brain, which further demonstrated the importance of GBA mutations as risk factors for Parkinson's disease. GBA mutations are being divided into two groups according to the resulting Gaucher's disease phenotype in homozygous or compound heterozygous individuals. Mild GBA mutations cause the adult Gaucher's disease Type I...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cellular transport and secretion
• Share to Glycosylation and Glycoproteins Research
• Share to Lysosomal Storage Disorders Research